| Title | AncestryDNA COVID-19 Host Genetic Study Identifies Three Novel Loci |
| DOI | https://doi.org/10.1101/2020.10.06.20205864 |
| Method | Genome wide association study |
| Curator 1 | jamiem |
| Curator 2 | rachelg |
| Population | Roberts |
| Published | Yes |
| Variant detail | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value |
| Variant | Roberts_rs111972040 | Male severity analysis | SRRM1, NCMAP, CLIC4, RCAN3, NIPAL3, RUNX3 | rs111972040 | Positive | Severe | 0.01 | 6.5 | 3.46e-03 |
| Variant | Roberts_rs111972040 | Female severity analysis | SRRM1, NCMAP, CLIC4, RCAN3, NIPAL3, RUNX3 | rs111972040 | Positive | Severe | 0.01 | 9.37 | 8.01e-07 |
| Variant | Roberts_rs111972040 | Meta Analysis | SRRM1, NCMAP, CLIC4, RCAN3, NIPAL3, RUNX3 | rs111972040 | Positive | Severe | 0.01 | 8.29 | 8.38e-09 |
| Variant | Roberts_rs11385942 | Meta Analysis | LZTFL1, SLC6A20, CCR9, FYCO1, CXCR6, XCR1, CCR2, CCR3 | rs11385942 | Positive | Severe | 0.08 | 1.43 | 2.00e-02 |
| Variant | Roberts_rs657152 | Meta Analysis | ABO | rs657152 | Positive | Severe | 0.36 | 1.26 | 2.20e-02 |
| Variant | Roberts_rs6668622 | Male susceptibility analysis | IVNS1ABP, SWT1, LOC107985239 | rs6668622 | Positive | Susceptibility | 0.31 | 0.69 | 3.28e-09 |
| Variant | Roberts_rs6668622 | Meta Analysis | IVNS1ABP, SWT1, LOC107985239 | rs6668622 | Positive | Susceptibility | 0.3 | 0.87 | 3.83e-05 |
| Variant | Roberts_rs73166864 | Male susceptibility analysis | immunoglobulin lambda locus, IGLL5, GNAZ, RSPH14, RAB36, BCR | rs73166864 | Positive | Susceptibility | 0.03 | 1.97 | 1.19e-05 |
| Variant | Roberts_rs73166864 | Female susceptibility analysis | Immunoglobulin lamba locus (IGLL5), GNAZ,RSPH14,RAB36,BCR | rs73166864 | Positive | Susceptibility | 0.02 | 1.55 | 2.21e-04 |
| Variant | Roberts_rs73166864 | Meta Analysis | Immunoglobulin lamba locus (IGLL5), GNAZ,RSPH14,RAB36,BCR | rs73166864 | Positive | Susceptibility | 0.02 | 1.7 | 1.56e-08 |
