Name | Paper | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value |
Horowitz_rs2236757 | Common genetic variants identify therapeutic targets for COVID-19 and individuals at high risk of severe disease | Meta analysis, External data | IFNAR2 | rs2236757 | Negative | Severe | 0.29 | 1.13 | 0.0002 |
Pairo-Castineira_rs2236757 | Genetic mechanisms of critical illness in Covid-19 | Critical COVID vs controls UKB | IFNAR2 | rs2236757 | Negative | Critical | None | 1.3 | 0.00000005 |
Horowitz_2_rs2236757 | Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease | Hospitalised COVID-19 vs negative/unknown | IFNAR2 | rs2236757 | positive | Susceptibility | 29.0 | 1.08 | 0.00007 |
Horowitz_2_rs2236757 | Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease | COVID-19 hospitalised vs not hospitalised | IFNAR2 | rs2236757 | positive | Severe | None | 1.08 | 0.00176 |