| Title | Common genetic variants identify therapeutic targets for COVID-19 and individuals at high risk of severe disease |
| DOI | https://doi.org/10.1101/2020.12.14.20248176 |
| Method | Genome wide association study |
| Curator 1 | fatima |
| Curator 2 | clherd |
| Population | Horowitz |
| Published | Yes |
| Variant detail | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value |
| Variant | Horowitz_rs12461764 | Meta analysis, External data | FPR1, HAS1 | rs12461764 | Positive | Severe | 0.35 | 1.18 | 1.00e-08 |
| Variant | Horowitz_rs143334143 | Meta analysis, External data | MHC (CCHCR1) | rs143334143 | Positive | Severe | 0.07 | 1.36 | 6.00e-04 |
| Variant | Horowitz_rs2109069 | Meta analysis, External data | DPP9 | rs2109069 | Positive | Severe | 0.31 | 1.06 | 1.00e-04 |
| Variant | Horowitz_rs2236757 | Meta analysis, External data | IFNAR2 | rs2236757 | Negative | Severe | 0.29 | 1.13 | 2.00e-04 |
| Variant | Horowitz_rs2531743 | Meta analysis, External data | SLC6A20, LOC107986082,LZTFL1, SACML1, CCR9, FYCO1, XCR1, CCR3, CCR1 | rs2531743 | Positive | Susceptibility | 0.42 | 1.06 | 9.00e-04 |
| Variant | Horowitz_rs4782327 | Meta analysis, External data | ACSF3 | rs4782327 | Positive | Severe | 0.22 | 1.17 | 8.00e-09 |
| Variant | Horowitz_rs73064425 | Meta analysis, External data | LZTFL1, CCR9, SLC6A20, FYCO1, CXCR6, XCR1, CCR1, CCR3 | rs73064425 | Positive | Severe | 0.07 | 1.42 | 7.00e-11 |
| Variant | Horowitz_rs79833209 | Meta analysis, External data | LOC105377700, CCNG1, NUDCD2, HMMR | rs79833209 | Positive | Severe | 0.02 | 1.54 | 2.00e-08 |
| Variant | Horowitz_rs9411378 | Meta analysis, External data | ABO | rs9411378 | Positive | Susceptibility | 0.23 | 1.12 | 6.00e-10 |
