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COHG-SA

Variant Detail

RSID rs35705950
HGVS NC_000011.10:g.1219991G>T
Chromosome 11
Start position1219991
Stop position1219991
Associated gene(s)MUC5B
Mutation typeSNP
Reference G
Alternative A/T
Associated allele T
Associated African Allele Frequency 0
Consequence Upstream transcript variant
Other population frequencies linkALFA rs35705950

Variants

NamePaperDescription of ComparisonGeneRSIDAssociationDisease StatusMAFStatistical Odds RatioStatistical P-value
Fadista_rs35705950 Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity >60 hospitalised vs pop contrl MUC5B rs35705950 Negative Severe None 0.86 0.0299
van Moorsel_rs35705950 The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population COVID cases vs control discov MUC5B rs35705950 negative Severe 0.04 0.42 0.023
van Moorsel_rs35705950 The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population COVID-19 cases vs controls UKB MUC5B rs35705950 negative Severe 0.08 0.66 0.001
van Moorsel_rs35705950 The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population Severe COVID vs controls Coh1 MUC5B rs35705950 negative Severe 0.1 0.81 0.039
van Moorsel_rs35705950 The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population Severe COVID vs controls Coh2 MUC5B rs35705950 negative Severe 0.1 0.79 0.03
van Moorsel_rs35705950 The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population Meta Analysis MUC5B rs35705950 negative Severe None 0.75 0.00000663

Papers

Paper
Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity
The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population