| Title | COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells | ||||||||
| DOI | https://doi.org/10.3390/genes11091010 | ||||||||
| Method | Whole exome sequencing | ||||||||
| Curator 1 | fatima | ||||||||
| Curator 2 | tsaone | ||||||||
| Population | Latini | ||||||||
| Published | Yes | ||||||||
| Variant detail | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value | |
|---|---|---|---|---|---|---|---|---|---|
| Variant | Latini_rs114363287 | COVID-19 positive vs GnomAD | TMPRSS2 | rs114363287 | Positive | Severe | 0.004 | None | 1.63e-02 |
| Variant | Latini_rs12329760 | COVID-19 positive vs GnomAD | TMPRSS2 | rs12329760 | Negative | Susceptibility | 0.17 | None | 2.28e-02 |
| Variant | Latini_rs1236237792 | COVID-19 positive vs GnomAD | Furin | rs1236237792 | Positive | Severe | 0.004 | None | |
| Variant | Latini_rs75603675 | COVID-19 positive vs GnomAD | TMPRSS2 | rs75603675 | Negative | Susceptibility | 0.36 | None | 4.46e-02 |
| Variant | Latini_rs769208985 | COVID-19 positive vs GnomAD | Furin | rs769208985 | Positive | Severe | 0.004 | None | 4.70e-03 |