| Title | Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 | ||||||||
| DOI | https://doi.org/10.1126/science.abd4570 | ||||||||
| Method | Whole genome / whole exome sequencing | ||||||||
| Curator 1 | clherd | ||||||||
| Curator 2 | fatima | ||||||||
| Population | Zhang | ||||||||
| Published | Yes | ||||||||
| Variant detail | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value | |
|---|---|---|---|---|---|---|---|---|---|
| Variant | Zhang_ rs181939581 | Critical COVID vs controls | IFNAR1 | rs181939581 | Positive | Critical | None | None | |
| Variant | Zhang_rs114566317 | Critical COVID vs controls | TICAM1 | rs114566317 | Positive | Critical | None | None | |
| Variant | Zhang_rs121434431 | Critical COVID-19 vs control | TLR3 | rs121434431 | Positive | Critical | None | None | |
| Variant | Zhang_rs199550479 | Critical COVID vs controls | IRF3 | rs199550479 | Positive | Critical | None | None | |
| Variant | Zhang_rs201782115 | Critical COVID vs controls | TICAM1 | rs201782115 | Positive | Critical | None | None | |
| Variant | Zhang_rs72552343 | Critical COVID vs controls | IFNAR1 | rs72552343 | Positive | Critical | None | None | |
| Variant | Zhang_rs746291558 | Critical COVID vs controls | IFNAR1 | rs746291558 | Positive | Critical | None | None | |
| Variant | Zhang_rs753582183 | Critical COVID vs controls | IRF7 | rs753582183 | Positive | Critical | None | None | |
| Variant | Zhang_rs756347258 | Critical COVID vs controls | IRF7 | rs756347258 | Positive | Critical | None | None | |
| Variant | Zhang_rs765147452 | Critical COVID vs controls | IRF7 | rs765147452 | Positive | Critical | None | None | |
| Variant | Zhang_rs970393690 | Critical COVID vs controls | IRF7 | rs970393690 | Positive | Critical | None | None |