| Population name | Roberts |
| Genome | GRCh37 |
| Consortium | Ancestry DNA |
| Super population | EUR, AMR |
| Population description | European ancestry (65%) Admixed African-European ancestry includes 100% African ancestry (6%) Admixed Amerindian ancestry also includes 100% Amerindian ancestry (11%) Other (18%) including Admixed East Asian-European ancestry also includes 100% East Asian ancestry |
| Population origin | Northern America |
| Case population size | 250 |
| Control population size | 1967 |
| Comorbidities | Asthma, Cardiovascular disease, diabetes, hypertension, autoimmune disease, rare health conditions (proportions specified in supplementary data) |
| Mean / median age | 56 |
| Sex | 105 male, 145 female |
| Severity | Severe |
| Sample source | Nasopharyngeal swab |
| Method | GWAS (Illumina genotyping array) |
| Bioinformatics | Linkage disequilibrum (LD)-pruned using PLINK 1.9 COVID-19 Host Genetics Initiative analysis plan version 1 using PLINK 2.0 for GWAS analysis |
| Imputation details | Haplotype Reference Consortium (HRC) reference panel Haplotypes : Eagle version 2.4.1 Software: Minimac4 (MAF)>0.01 R2>0.30 |
| Limitations | Participants required to fill out a survey therefore cases that were very severe or fatal would not be included Participants restricted to European ancestry due to small numbers from other ancestral groups No independent replication cohort to determine if results are reproducible. Did not assess indels |