Title | A Chinese host genetic study discovered IFNs and causality of laboratory traits on COVID-19 severity |
DOI | https://doi.org/10.1016/j.isci.2021.103186 |
Method | Microarray, Genome wide association study |
Curator 1 | fatima |
Curator 2 | admin |
Population | Zhu |
Published | Yes |
| Variant detail | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value |
Variant | Zhu_rs11032789 | Severe vs Apo A levels | EHF | rs11032789 | positive | Severe | 0.04 | None | 6.40e-10 |
Variant | Zhu_rs1801020 | Severe vs APTT (activated partial thromboplastin time) levels | F12/SLC34A1 | rs1801020 | positive | Severe | 0.254 | None | 4.13e-16 |
Variant | Zhu_rs28946889 | Severity vs Total Bilirubin level | UGT1A complex | rs28946889 | positive | Severe | 0.4 | None | 5.08e-14 |
Variant | Zhu_rs28946889 | Severity vs Total Bilirubin level | UGT1A complex | rs28946889 | positive | Severe | 0.4 | None | 1.51e-16 |
Variant | Zhu_rs56393506 | Severity vs Lipoprotein A | LPA | rs56393506 | positive | Severe | 0.114 | None | 1.97e-14 |