| Title | The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population | ||||||||
| DOI | https://doi.org/10.3389/fmed.2021.668024 | ||||||||
| Method | PCR-based SNP genotyping assay | ||||||||
| Curator 1 | fatima | ||||||||
| Curator 2 | admin | ||||||||
| Population | van Moorsel | ||||||||
| Published | Yes | ||||||||
| Variant detail | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value | |
|---|---|---|---|---|---|---|---|---|---|
| Variant | van Moorsel_rs35705950 | COVID cases vs control discov | MUC5B | rs35705950 | negative | Severe | 0.04 | 0.42 | 2.30e-02 |
| Variant | van Moorsel_rs35705950 | COVID-19 cases vs controls UKB | MUC5B | rs35705950 | negative | Severe | 0.08 | 0.66 | 1.00e-03 |
| Variant | van Moorsel_rs35705950 | Severe COVID vs controls Coh1 | MUC5B | rs35705950 | negative | Severe | 0.1 | 0.81 | 3.90e-02 |
| Variant | van Moorsel_rs35705950 | Severe COVID vs controls Coh2 | MUC5B | rs35705950 | negative | Severe | 0.1 | 0.79 | 3.00e-02 |
| Variant | van Moorsel_rs35705950 | Meta Analysis | MUC5B | rs35705950 | negative | Severe | None | 0.75 | 6.63e-06 |