| Population name | Kuo |
| Genome | Not specified |
| Consortium | Not specified |
| Super population | EUR |
| Population description | England |
| Population origin | Northern and Western Europe |
| Case population size | 622 |
| Control population size | 322948 |
| Comorbidities | APOE e4e4 risk allele Dementia (0.22%);Hypertension (32.42%);Coronary artery disease (8.7%);Type 2 diabetes (5.36%) |
| Mean / median age | 68 ± 8 |
| Sex | 55% (176951) female |
| Severity | Severe |
| Sample source | Nasopharyngeal swab |
| Method | UK Biobank participants, genotyped for ApoE (UK Biobank axiom array) with a positive COVID-19 result were compared to participants who did not test positive over the period 16 March - 26 April 2020. |
| Bioinformatics | A logistic regression model was used to compare e4e4 genotypes to e3e3 for COVID-19 positivity status, adjusted for sex and age. Genotyping array type and the top five genetic principal components (accounting for possible population admixture). |
| Imputation details | Not specified |
| Limitations | Letter to the editor with little detail on methods and population specifics. Authors focused on two variants only. |