| Title | Genome-wide association study of COVID-19 severity among the Chinese population |
| DOI | https://doi.org/10.1038/s41421-021-00318-6 |
| Method | Genome wide association study |
| Curator 1 | fatima |
| Curator 2 | admin |
| Population | Li |
| Published | Yes |
| Variant detail | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value |
| Variant | Li_rs10831496 | Critical vs Controls | CTSC (GRM5) | rs10831496 | positive | Severe | None | 1.77 | 7.17e-04 |
| Variant | Li_rs10831496 | Meta Analysis | CTSC (GRM5) | rs10831496 | positive | Severe | None | 1.66 | 4.04e-08 |
| Variant | Li_rs12329760 | Meta-analysis (T allele) | TMPRSS2 | rs12329760 | negative | Severe | None | 0.81 | 1.00e-02 |
| Variant | Li_rs17000900 | Meta Analysis | MX1 | rs17000900 | negative | Severe | None | 0.73 | 5.00e-03 |
| Variant | Li_rs1712779 | critical vs controls | NNMT, CADM1, ZBTB16, RBM1, REX02,C11orf71 (NXPE2) | rs1712779 | negative | Severe | None | 0.51 | 6.13e-04 |
| Variant | Li_rs1712779 | meta-analysis | NNMT, CADM1, ZBTB16, RBM1, REX02,C11orf71 (NXPE2) | rs1712779 | negative | Severe | None | 0.49 | 1.38e-08 |
| Variant | Li_rs2071430 | meta-analysis | MX1 | rs2071430 | negative | Severe | None | 0.65 | 3.80e-06 |
| Variant | Li_rs2109069 | severe vs control (Huoshenshan cohort) | DPP9 | rs2109069 | positive | Severe | None | 1.33 | 3.20e-02 |
| Variant | Li_rs2109070 | combined meta-analysis | DPP9 | rs2109070 | positive | Severe | None | 1.33 | 4.20e-03 |
| Variant | Li_rs657152 | combined metaanalysis | ABO | rs657152 | positive | Severe | None | 1.27 | 1.70e-03 |
