| Population name | Hubacek |
| Genome | not specified |
| Consortium | Institutes and Universities in the Czech Republic |
| Super population | EUR |
| Population description | 246 symptomatic (without requiring hospitalisation and 164 asymptomatic COVID-19 positive cases during the first wave (app. March 2020 – June 2020) of the disease in the Czech Republic. All cases completely recovered with no adverse events. |
| Population origin | Czech Republic |
| Case population size | 410 |
| Control population size | 2559 |
| Comorbidities | 7.8% diabetes, 13.3% hypertensive |
| Mean / median age | 44 ± 15 |
| Sex | 54.7% female |
| Severity | Mild |
| Sample source | TBD |
| Method | DNA was isolated from EDTA-treated blood. The ACE I/D polymorphism was genotyped and PCR products of ~ 490 bp and ~ 200 bp characterise the I and D alleles, respectively. All D/D subjects were re-genotyped with ACE I-specific oligonucleotides to avoid the misgenotyping of some I/D heterozygotes as D/D homozygotes. |
| Bioinformatics | Statistical analysis was performed using the www.socscistatistics.com tools |
| Imputation details | NA |
| Limitations | The ACE I/D polymorphism effect on COVID-19 outcomes have varied outcomes from different papers (Gomez et al 2020 showed the D/D genotype affecting COVID-19 severity outcomes) |