| Population name | Chamnanphon |
| Genome | GRCh37 |
| Consortium | Universities and Hospitals in Thailand |
| Super population | EAS |
| Population description | Samples were obtained from both biobank samples and cases admitted to King Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand between February 2020 to March 2021. Clinical characterostics and data were assessed and cases were classified into four conditions mild, moderate, severe and critical |
| Population origin | Thailand |
| Case population size | 212 |
| Control population size | 36 |
| Comorbidities | Diabetes, Dyslipidemia, Chronic kidney disease, Cardiovascular disease, lung and liver disease, cancer, immunocompromised system |
| Mean / median age | 44 |
| Sex | 91 males 157 females |
| Severity | Combination |
| Sample source | Nasopharyngeal swab |
| Method | Genomic DNA was analysed with the AxiomTM Human Genotyping SARS-COV-2 Array (Thermo Fisher Scientific) |
| Bioinformatics | Genotype calling from intensity data file was performed with Axiom Analysis Suite (AxAS) version 5.1.1 software using default parameters. Quality control (QC) and PCA was carried out following Ricopili pipeline (Lam et al 2020). SNPs were pruned to minimize LD between SNPs with the criteria of R2 < 0.2, and the number of SNPs in the window for pruning was 200 until there were less than 100,000 SNPs. SAIGE was applied for association analysis in GWAS using a logistic mixed-effects model. LD blocks using LDBlockShow were obtained, and genes residing in the blocks which contained SNPs with statistical significance were acquired using the University of California, Santa Cruz (UCSC) Genome Browser. |
| Imputation details | Genotype imputation was done for chromosomes 1–22 using Michigan Imputation Server and the reference panel used was Genome Asia Pilot (GAsP) |
| Limitations | The limitation of this study was the relatively small sample size |