Population

Population name Pehlivan
Genome not specified
Consortium University of Istanbul
Super population SAS
Population description Patients diagnosed with COVID-19 between April and June 2020 who were admitted to the COVID-19 center of a university hospital, and 100 healthy individuals without any known were included as controls. Healthy controls consisted of individuals who were negative for Sars-CoV-2 antibody (Sars-Cov-2 IgM, IgG) and were negative in two PCR results taken with an interval of 48 hours. Patients included those that were diagnosed with COVID-19 who show false negativity with initial examinations before hos
Population origin Istanbul, Turkey
Case population size 70
Control population size 100
Comorbidities not specified
Mean / median age not specified
Sex not specified
Severity Susceptibility
Sample source Nasopharyngeal and Clinical characteristics
Method PCR and/or RFLP was used to isolate DNA samples from blood leukocytes at the time of diagnosis. MBL2-rs1800450, NOS3-rs1799983 and NOS3-intron 4 VNTR gene polymorphisms were analyzed.
Bioinformatics Logistic regression was used to analyse statistical differences analysis between groups. The adjusted odds ratios (ORs) were calculated with a logistic regression model that checked for sex and age and are reported with 95% confidence intervals (CIs). Differences between the patients’ group were compared using the chi-square test and the Fisher exact test when required. A p-value of less than 0.05 was accepted as significant.
Imputation details NA
Limitations a. Limited patient population, b. No MBL serum levels were recorded