Name | Paper | Description of Comparison | Gene | RSID | Association | Disease Status | MAF | Statistical Odds Ratio | Statistical P-value |
Horowitz_rs143334143 | Common genetic variants identify therapeutic targets for COVID-19 and individuals at high risk of severe disease | Meta analysis, External data | MHC (CCHCR1) | rs143334143 | Positive | Severe | 0.07 | 1.36 | 0.0006 |
Pairo-Castineira_rs143334143 | Genetic mechanisms of critical illness in Covid-19 | Critical COVID vs controls UKB | CCHCR1 | rs143334143 | Positive | Critical | None | 1.8 | 0.0000000000000000088 |
Pairo-Castineira_rs143334143 | Genetic mechanisms of critical illness in Covid-19 | hospitalised vs controls | CCHCR1 | rs143334143 | Positive | Severe | None | 1.3 | 0.00000000015 |
Horowitz_2_rs143334143 | Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease | COVID-19 positive vs COVID-19 negative or unknown | CCHCR1 | rs143334143 | positive | Susceptibility | 7.0 | 1.06 | 0.0002 |
Horowitz_2_rs143334143 | Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease | COVID-19 severe vs not hospitalised | CCHCR1 | rs143334143 | positive | Severe | None | 1.14 | 0.0306 |