COVID image

COHG-SA

Variant Detail

RSID rs74956615
HGVS NC_000019.9:g.10427721T>A
Chromosome 19
Start position10317045
Stop position10317045
Associated gene(s)RAVER1, FDX2, ICAM1, ICAM4, ICAM5, ZGLP1, ICAM3, TYK2
Mutation typeTagged SNP
Reference T
Alternative A/C
Associated allele A
Associated African Allele Frequency 0.0003
Consequence 3 Prime UTR Variant
Other population frequencies linkALFA rs74956615

Variants

NamePaperDescription of ComparisonGeneRSIDAssociationDisease StatusMAFStatistical Odds RatioStatistical P-value
COVID-19 HGI_rs74956615 Mapping the human genetic architecture of COVID-19 Hospitalised vs Controls RAVER1, FDX2, ICAM1, ICAM4, ICAM5, ZGLP1, ICAM3, TYK2 rs74956615 Positive Severe 0.048 1.266 0.00000000055
COVID-19 HGI_rs74956615 Mapping the human genetic architecture of COVID-19 Critical vs Controls RAVER1, FDX2, ICAM1, ICAM4, ICAM5, ZGLP1, ICAM3, TYK2 rs74956615 Positive Critical 0.048 1.434 0.00000000000971
Pairo-Castineira_rs74956615 Genetic mechanisms of critical illness in Covid-19 Critical COVID vs controls UKB RAVER1, FDX2, ICAM1, ICAM4, ICAM5, ZGLP1, ICAM3, TYK2 rs74956615 Positive Critical None 1.6 0.000000023

Papers

Paper
Mapping the human genetic architecture of COVID-19
Genetic mechanisms of critical illness in Covid-19