Alleles / Haplotypes

NamePaperDescription of ComparisonGeneGene IDAssociationDisease StatusStatistical Odds RatioStatistical P-value
12q22 (93426633–93446082)
Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population Moderate, severe or critical vs mild COVID-19 positive controls EEA1, LINC02412, LOC643339 ENSG00000102189 positive Severe 0.31 4.35e-06
5q32 (148710242–148768047)
Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population COVID-19 positive vs exposed negative controls IL17B, AFAP1L1, GRPEL2, PCYOX1L, ABLIM3, BX640700, CSNK1A1, L26953, MIR143 ENSG00000127743 (IL17B) positive Susceptibility 0.02 6.87e-06
9q21.13 (77748151–77762449)
Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population COVID-19 positive vs exposed negative controls OSTF1, C9orf41, BC043649, NMRK1 - positive Susceptibility 0.13 9.51e-06
Blood group A
Genome-wide association study of COVID-19 severity among the Chinese population Severe vs controls ABO ENSG00000175164 positive Severe 1.22 3.20e-04
Blood group O
Genome-wide association study of COVID-19 severity among the Chinese population Severe vs controls ABO ENSG00000175164 negative Severe 0.83 1.50e-03
HLA B*58:01
Genome-wide association study of COVID-19 severity among the Chinese population Severe vs controls HLA B ENSG00000234745 positive Severe Not available 1.00e-02
HLA C*3:02
Genome-wide association study of COVID-19 severity among the Chinese population Severe vs controls HLA C ENSG00000204525 positive Severe Not available 3.00e-02
HLA-E*0101/0103 allelic variant
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 HLA-E*0101/01/03 and ICU HLA-E ENSG00000204592 positive Critical 2.7 1.00e-02
HLA-E*0101/0103 allelic variant
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 Cases with HLA-E*0101/01/03 allele with hospitalisation HLA-E ENSG00000204592 positive Severe 2.1 1.00e-02
NKG2C deletion allele
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 Cases with KLRC2 del allele with hospitalisation CD94/KLRC2 ENSG00000205809 positive Severe 2.6 6.00e-04
NKG2C deletion allele
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 Cases with KLRC2 del allele with hospitalisation and ICU CD94/KLRC2 ENSG00000205809 positive Critical 7.1 1.00e-04