Name | Paper | Description of Comparison | Gene | Gene ID | Association | Disease Status | Statistical Odds Ratio | Statistical P-value |
12q22 (93426633–93446082) |
Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population |
Moderate, severe or critical vs mild COVID-19 positive controls |
EEA1, LINC02412, LOC643339 |
ENSG00000102189 |
positive |
Severe |
0.31
|
4.35e-06
|
5q32 (148710242–148768047) |
Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population |
COVID-19 positive vs exposed negative controls |
IL17B, AFAP1L1, GRPEL2, PCYOX1L, ABLIM3, BX640700, CSNK1A1, L26953, MIR143 |
ENSG00000127743 (IL17B) |
positive |
Susceptibility |
0.02
|
6.87e-06
|
9q21.13 (77748151–77762449) |
Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population |
COVID-19 positive vs exposed negative controls |
OSTF1, C9orf41, BC043649, NMRK1 |
- |
positive |
Susceptibility |
0.13
|
9.51e-06
|
Blood group A |
Genome-wide association study of COVID-19 severity among the Chinese population |
Severe vs controls |
ABO |
ENSG00000175164 |
positive |
Severe |
1.22
|
3.20e-04
|
Blood group O |
Genome-wide association study of COVID-19 severity among the Chinese population |
Severe vs controls |
ABO |
ENSG00000175164 |
negative |
Severe |
0.83
|
1.50e-03
|
HLA B*58:01 |
Genome-wide association study of COVID-19 severity among the Chinese population |
Severe vs controls |
HLA B |
ENSG00000234745 |
positive |
Severe |
Not available
|
1.00e-02
|
HLA C*3:02 |
Genome-wide association study of COVID-19 severity among the Chinese population |
Severe vs controls |
HLA C |
ENSG00000204525 |
positive |
Severe |
Not available
|
3.00e-02
|
HLA-E*0101/0103 allelic variant |
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 |
HLA-E*0101/01/03 and ICU |
HLA-E |
ENSG00000204592 |
positive |
Critical |
2.7
|
1.00e-02
|
HLA-E*0101/0103 allelic variant |
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 |
Cases with HLA-E*0101/01/03 allele with hospitalisation |
HLA-E |
ENSG00000204592 |
positive |
Severe |
2.1
|
1.00e-02
|
NKG2C deletion allele |
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 |
Cases with KLRC2 del allele with hospitalisation |
CD94/KLRC2 |
ENSG00000205809 |
positive |
Severe |
2.6
|
6.00e-04
|
NKG2C deletion allele |
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19 |
Cases with KLRC2 del allele with hospitalisation and ICU |
CD94/KLRC2 |
ENSG00000205809 |
positive |
Critical |
7.1
|
1.00e-04
|